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Pancreatic Proteolytic Enzyme Therapy Fails To Increase Survival or Quality of Life Compared to Conventional Gemcitabine Cytotoxic Therapy.

 ....those who chose gemcitabine-based chemotherapy survived more than three times as long (14.0 v 4.3 months) and had better quality of life than those who chose proteolytic enzyme treatment.

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Methodology for Clinical Trials in Integrative Oncology by Andrew Vickers PhD.

Andrew Vickers has written a series of articles on methodology of clinical trials of integrative medicine, including issues such as randomization, early phase clinical trials, accrual and quality of life assessment. All of these articles are now available open access (i.e. free-of-charge) via PubMed Central. Simply go to Medline(http://www.ncbi.nlm.nih.gov/sites/entrez)  and run the following search:  "J Soc Integr Oncol"[Journal] AND Vickers a[au] Click on an article that interests you to see the abstract, then click on “free author manuscript in PubMed Central” towards the top write for the free text.

CONTENT

1: Phase II designs...
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A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects.

Cancer patients should be made aware of the fact that botanical agents produce more complex effects than assumed, and may depress as well as enhance immune function.

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Safety and pharmacokinetic trial of docetaxel plus an Astragalus-based herbal formula for non-small cell lung cancer patients.

Jinfukang did not alter the pharmacokinetics of docetaxel nor appear to affect survival in this study.

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Evaluation of widely consumed botanicals as immunological adjuvants

Some, but not all, botanicals purported to be immune stimulants had adjuvant activity in our model. PSK and Astragalus were surprisingly active and are being further fractionated to identify the most active adjuvant components.

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Does acupuncture work for pain??

Systematic review of randomised clinical trials with acupuncture, placebo acupuncture, and no acupuncture groups.

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Massage and Acupuncture Relieve Pain After Cancer Surgery

If you or loved one face surgery for colon cancer, you may want to consider adding massage and acupuncture to the usual care provided. Here's what a recent study recommends.

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Yoga Improves Pain and Fatigue

On the day after a day during which women practiced more yoga, they experienced significantly lower levels of pain and fatigue, and higher levels of invigoration, acceptance, and relaxation.

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Personalized Medicine

Personalized medicine is inherent to integrative oncology. An individualized holistic care plan provides optimum treatment for a cancer patient, using the best evidence from all treatment domains.

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Selenium and Vitamin E fail to Prevent Prostate Cancer.

Huge disappointment: Selenium and Vitamin E fail to Prevent Prostate Cancer.

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Research Principles for Integrative Oncology

Can complementary therapies for cancer patients be evaluated by clinical trials?

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USC study finds that green tea blocks benefits of cancer drug

Contrary to popular assumptions about the health benefits of green tea, researchers at the University of Southern California (USC) have found that the widely used supplement renders a cancer drug used to treat multiple myeloma and mantle cell lymphoma completely ineffective in treating cancer.

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Acupuncture Reduces Dysfunction after Head and Neck Cancer Surgery

Acupuncture reduces symptoms after head and neck cancer surgery.
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Acupuncture Relieves Vasomotor Symptoms in Breast Cancer Patients

For breast cancer patients with treatment-related vasomotor symptoms, acupuncture may offer an effective, durable alternative to drug therapy with fewer side effects, researchers found. 

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Acupuncture Associated With Neuronal Activation and Physiological Responses

Acupuncture at the point LI-2 is associated with neuronal activation and an increase in saliva production. 
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